Research Activities

Role of old pharmaceuticals in new indications

Conventional medicine focuses mainly on the use of pharmaceuticals in the treatment of somatic and psychiatric disease at the present time. Pharmaceuticals are registered for specific indications, and the only way to deviate from this list is to prescribe a medicine 'off label', which means that there is no clinical research available to support its use in the 'off label' condition. The SIA system allows us to think beyond the traditional registered indications and explore the use of old medicines in new indications as well as target the mechanisms for new drug innovation.

Antibiotic resistance is one of the major challenges in medicine today. The hypothesis and its extension, the SIA system, provide new insight into the mechanisms by which microbes can use the central nervous system/endocrine/vascular system to bypass the immune system. However, this also gives us a unique opportunity to find solutions to the vascular damage/autoimmunity and other pathology that may arise.

Role of SIA system in pharmaceutical side effects

Many of the side effects seen with pharmaceuticals may be due to problems related to the SIA system and markers may be found which can identify those patients who have a high probability of having an adverse event. We may also be able to suggest new solutions which ameliorate the side effects.

Role of nutrients in the SIA system

SIA system function is dependent upon B vitamins/gut bacteria, therefore nutrition and the use of probiotics following infection have a major role to play in treatment.

Role of other periphery services

Stress management/psychotherapy may help to prevent the negative effects of stress on the immune system. Dental hygiene is important in preventing infection, which may spread to other sites in the body. Exercise has a direct effect on insulin sensitivity.

We hope that you will join us in exploring the SIA system and its application in clinical trials (human studies). At the present time we do not have the funding for such, but hope that government/corporations will support the cross scientific research necessary to identify those disease states, which may benefit from SIA system intervention.